| 2023 |
| Fri., Nov. 10 | vs. Wayne County | W 36-0 | 1st Round Playoffs | | Fri., Nov. 17 | vs. Gautier | L 34-36 | 2nd Round Playoffs |
| 2020 |
| Fri., Nov. 6 | @ Poplarville | L 17-62 | 1st Round Playoffs |
| 2018 |
| Fri., Nov. 2 | vs. Lawrence County | W 38-35 | 1st Round Playoffs | | Fri., Nov. 9 | @ West Lauderdale | L 14-42 | 2nd Round Playoffs |
| 2017 |
| Fri., Nov. 3 | @ Pass Christian | W 14-7 | 1st Round Playoffs | | Fri., Nov. 10 | vs. Purvis | L 21-41 | 2nd Round Playoffs |
| 2016 |
| Fri., Nov. 4 | vs. Northeast Jones | W 57-29 | 1st Round Playoffs | | Fri., Nov. 11 | vs. East Central | W 31-14 | 2nd Round Playoffs | | Fri., Nov. 18 | @ Purvis | W 28-7 | 3rd Round Playoffs | | Fri., Nov. 25 | @ Poplarville | L 14-42 | Semi-finals Playoffs |
| 2015 |
| Fri., Nov. 6 | @ Purvis | L 13-14 | 1st Round Playoffs |
| 2014 |
| Fri., Nov. 7 | vs. Vancleave | L 50-53 | 1st Round Playoffs |
| 2013 |
| Fri., Nov. 8 | @ Forrest County AHS | L 7-42 | 1st Round Playoffs |
| 2011 |
| Fri., Nov. 4 | vs. Saint Stanislaus | W 38-33 | 1st Round Playoffs | | Fri., Nov. 11 | @ Quitman | L 14-35 | 2nd Round Playoffs |
| 2010 |
| Fri., Nov. 5 | @ Laurel | L 16-41 | 1st Round Playoffs |
| 2009 |
| Fri., Nov. 6 | @ North Pike | L 21-41 | 1st Round Playoffs |
| 2007 |
| Fri., Nov. 9 | @ Laurel | L 21-48 | 1st Round Playoffs |
| 2001 |
| Fri., Nov. 9 | @ Lawrence County | W 23-20 | 1st Round Playoffs | | Fri., Nov. 16 | vs. Northeast Jones | L 7-14 | 2nd Round Playoffs |
| 2000 |
| Fri., Nov. 10 | vs. Noxubee County | W 24-8 | 1st Round Playoffs | | Fri., Nov. 17 | @ Cleveland | L 6-61 | 2nd Round Playoffs |
| 1988 |
| Fri., Nov. 11 | @ Stone | L 0-34 | 1st Round Playoffs |
| 1986 |
| Fri., Nov. 14 | vs. Eupora | W 13-6 | 1st Round Playoffs | | Fri., Nov. 21 | vs. Mendenhall | L 0-30 | 2nd Round Playoffs |
|
| Florence Playoff Totals |
| Record |
10-16-0 557-795 |
| Home Record | 7-5 |
| Away Record | 3-11 |
|
