| 2025 |
| Fri., Nov. 7 | vs. Okolona | - | 1st Round Playoffs |
| 2024 |
| Fri., Nov. 8 | vs. Sacred Heart | W 35-14 | 1st Round Playoffs | | Fri., Nov. 15 | @ Velma Jackson | L 12-42 | 2nd Round Playoffs |
| 2023 |
| Fri., Nov. 3 | vs. Leake County | W 42-0 | 1st Round Playoffs | | Fri., Nov. 10 | @ Resurrection | L 16-33 | 2nd Round Playoffs |
| 2022 |
| Fri., Nov. 11 | @ Biggersville | L 0-48 | 1st Round Playoffs |
| 2021 |
| Fri., Nov. 12 | @ Tupelo Christian Prep | L 0-45 | 1st Round Playoffs |
| 2019 |
| Fri., Nov. 15 | @ Resurrection | L 20-54 | 1st Round Playoffs |
| 2017 |
| Fri., Nov. 3 | vs. Walnut | W 44-24 | 1st Round Playoffs | | Fri., Nov. 10 | @ Winona | L 22-62 | 2nd Round Playoffs |
| 2016 |
| Fri., Nov. 4 | @ Walnut | L 12-14 | 1st Round Playoffs |
| 2015 |
| Fri., Nov. 6 | @ OBannon | L 20-22 | 1st Round Playoffs |
| 2014 |
| Fri., Nov. 7 | vs. Eupora | L 44-51 | 1st Round Playoffs |
| 2013 |
| Fri., Nov. 8 | @ Baldwyn | L 22-44 | 1st Round Playoffs |
| 2011 |
| Fri., Nov. 4 | @ Bruce | L 0-44 | 1st Round Playoffs |
| 2010 |
| Fri., Nov. 5 | @ West Bolivar | L 0-52 | 1st Round Playoffs |
| 2009 |
| Fri., Nov. 6 | vs. George | W 20-7 | 1st Round Playoffs | | Fri., Nov. 13 | @ Baldwyn | L 12-47 | 2nd Round Playoffs |
| 2008 |
| Fri., Nov. 7 | @ Walnut | L 0-38 | 1st Round Playoffs |
| 2007 |
| Fri., Nov. 9 | vs. Riverside | L 26-28 | 1st Round Playoffs |
| 2006 |
| Fri., Nov. 3 | vs. Bruce | L 8-22 | 1st Round Playoffs |
| 2005 |
| Fri., Nov. 11 | vs. Mantachie | W 40-6 | 1st Round Playoffs | | Fri., Nov. 18 | vs. Calhoun City | L 6-34 | 2nd Round Playoffs |
| 2004 |
| Fri., Nov. 5 | @ Leflore County | L 0-22 | 1st Round Playoffs |
| 2003 |
| Fri., Nov. 7 | @ Eupora | L 6-42 | 1st Round Playoffs |
| 2001 |
| Fri., Nov. 9 | @ Leflore County | L 6-36 | 1st Round Playoffs |
| 1949 |
| Fri., Nov. 11 | Sallis | L 7-13 | 1st Round Playoffs |
|
| West Tallahatchie Playoff Totals |
| Record |
5-21-0 420-844 |
| Home Record | 5-4 |
| Away Record | 0-16 |
|
