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Louisville Wildcats
| Louisville High School 
 200 Ivy Avenue Louisville, MS Stadium: R.E. Hinze Stadium Colors: Maroon & White Coach:  | 
	
Louisville vs. Lafayette
| Date | Opponent | Score | |
| 9/16/2016 (Fri) | @ Lafayette | L 7-42 | |
| 11/11/2016 (Fri) | @ Lafayette | L 7-24 | 2nd Round Playoffs | 
| 9/18/2015 (Fri) | vs. Lafayette | L 10-27 | |
| 11/18/2011 (Fri) | @ Lafayette | L 6-28 | 3rd Round Playoffs | 
| 11/12/2010 (Fri) | @ Lafayette | L 12-44 | 2nd Round Playoffs | 
| 11/13/2009 (Fri) | @ Lafayette | L 6-14 | 2nd Round Playoffs | 
| 9/8/2006 (Fri) | vs. Lafayette | L 21-23 | |
| 9/16/2005 (Fri) | @ Lafayette | L 7-31 | |
| 11/12/1999 (Fri) | vs. Lafayette | W 21-0 | 1st Round Playoffs | 
| 11/22/1991 (Fri) | @ Lafayette | W 21-14 | 2nd Round Playoffs | 
Louisville has won 2 and scored 118 points Lafayette has won 8 and scored 247 points with 0 being tied  | 
| # Forfeit * Region Game | 
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      Great Moments in Alabama High School Football History
	  
Murphy and Theodore battled through seven overtimes before the Panthers came out on top 33-26 in 1979.
Murphy and Theodore battled through seven overtimes before the Panthers came out on top 33-26 in 1979.