| 2025 |
| Fri., Oct. 31 | vs. Scranton | W 43-16 | 1st Round Playoffs | | Fri., Nov. 7 | @ Wilkes-Barre | L 14-42 | 2nd Round Playoffs |
| 2024 |
| Fri., Nov. 1 | vs. Hazleton Area | W 15-6 | 1st Round Playoffs | | Fri., Nov. 8 | @ Wilkes-Barre | W 14-0 | 2nd Round Playoffs | | Fri., Nov. 15 | vs. State College | L 14-75 | 3rd Round Playoffs |
| 2021 |
| Fri., Nov. 5 | vs. Altoona | W 36-14 | 1st Round Playoffs | | Fri., Nov. 12 | State College | L 14-17 | 2nd Round Playoffs |
| 2020 |
| Fri., Oct. 30 | Altoona | L 14-29 | 1st Round Playoffs |
| 2019 |
| Fri., Nov. 1 | @ Deleware Valley | L 6-48 | 1st Round Playoffs |
| 2018 |
| | @ Hazleton | L 13-47 | 1st Round Playoffs |
| 2017 |
| | vs. Hazleton | L 27-28 | 1st Round Playoffs |
| 2016 |
| | vs. Hazleton | W 48-14 | 1st Round Playoffs | | | vs. Delaware Valley | W 55-21 | 2nd Round Playoffs | | | vs. State College | W 35-28 | 3rd Round Playoffs | | | @ Pittsburgh Central Catholic | L 21-62 | Semi-finals Playoffs |
| 2015 |
| | @ Emmaus | L 22-61 | 1st Round Playoffs |
| 2010 |
| | @ Nazareth | L 24-63 | 1st Round Playoffs |
| 1997 |
| | @ Wyoming Valley West | L 14-34 | 1st Round Playoffs |
| 1995 |
| | vs. Tunkhannock | W 56-6 | 1st Round Playoffs | | | @ Wyoming Valley West | W 26-21 | 2nd Round Playoffs | | | vs. Lower Dauphin | L 0-36 | 3rd Round Playoffs |
| 1994 |
| | vs. West Scranton | W 28-7 | 1st Round Playoffs | | | vs. Cumberland Valley | L 10-12 | 2nd Round Playoffs |
| 1986 |
| | vs. Mount Carmel | W 38-0 | Championship Game |
|
| Williamsport Playoff Totals |
| Record |
11-13-0 587-687 |
| Home Record | 9-4 |
| Away Record | 2-7 |
|
